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WHAT IT IS Orlane's concentrate smooths, evens, and perfects the skin, reducing imperfections, blemishes, and wrinkles. The complexion is left looking fresh, even, and younger. 1 oz. Made in USA. WHO IT'S FOR All skin types ACTIVE INGREDIENTS Niacinamide - aka Vitamin B3 - is an essential active ingredient to combat skin blemishes, excess sebum production, dark spots, and wrinkles. Cosmetics - Heritage Treatment > Orlane > Saks Fifth Avenue. Orlane.