WHAT IT ISNoble Panacea 's The Exceptional RetiNAD+ Renewal Booster is proven to smooth, firm, and plump skin in just 10 days. A powerful complex of three retinoid forms and NAD+ helps target fine lines and wrinkles, loss of firmness, and elasticity for visibly renewed skin. Noble Panacea's patented OSMV™ Technology is what ensures product precision, control, and an exceptional level of skin tolerance for ingredients that are traditionally viewed as harsh or aggressive. 0. 13 oz. Made in USA. WHAT IT DOESIngredients are released progressively through micro-dosing, and in a programmed sequence: first a marine bio-retinoid, then retinol, and lastly retinal, building from gentle to more potent forms of Vitamin A alternatives and derivatives. NAD+ is released consistently throughout, amplifying retinoid activity, followed by the final delivery of niacinamide to soothe and calm skin. ACTIVE INGREDIENTSMarine Bio-Retinoid: Natural alternative to retinoid that mimics the anti-aging benefits without irritation. Retinol: Accelerates cell turnover and boosts collagen synthesis. Retinal: Reduces fine lines and wrinkles by stimulating collagen production. NAD+: Upregulates retinoid binding, assists with DNA repair to slow signs of aging. Niacinamide: Calms irritation, reduces redness, strengthens the skin barrier to alleviate future sensitivity. HOW TO USE ITRecommended for use in the evening. Apply before or mix with serum, pressing into a freshly cleansed face and neck, avoiding the eye area. Follow with moisturizer. Ensure SPF protection in the morning. RESEARCH RESULTSAfter 10 days of use: 18% reduction in wrinkle volume loss*. 90% agreed their skin appeared renewed**. 88% said their skin texture had improved**. 93% confirmed their skin was calm and without redness or irritation**. *Based on an independent clinical trial, with 35 (female and male) participants, measured by Primos. **Based on a consumer study, with 35 (female and male) participants.